Bromination of Substituted Anilides

Abstract

The rate of bromination of Aromatic compounds has been found to vary greatly, some reactions being almost instantaneous, e.g. bromination of phenol with three molecules of bromine to form symmetrical tribromo-phenol, whilst some are very slow, occasionally months passing before one molecule completely enters. In all cases the rate is greatly increased if a halogen carrier, e.g. iodine (Muller 1862) red phosphorus (Volhard 1885) or hydrogen chloride (Lapworth 1903) etc., is present.