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Kinetic studies of the hydrolysis of α-amino acid esters

dc.contributor.authorMain, Lyndsay
dc.date.accessioned2011-03-10T22:57:21Z
dc.date.accessioned2022-10-25T04:58:29Z
dc.date.available2011-03-10T22:57:21Z
dc.date.available2022-10-25T04:58:29Z
dc.date.copyright1966
dc.date.issued1966
dc.description.abstractThe rate of acid-catalysed hydrolysis of ethyl glycinate has been shown to be considerably slower than that of ethyl acetate, contrary to previously published results. The rates of alkaline hydrolysis of some ethyl esters of common amino acids have been obtained, and are in agreement with results in the literature. Some aromatic aldehydes, carbon dioxide, and imidazole have been shown to be efficient catalysts for the hydrolysis of the p-nitrophenyl esters of glycine, leucine, and phenylalanine. Both the aromatic aldehydes and carbon dioxide appear to catalyse the reactions by forming addition compounds with the unprotonated amino group of the ester. In the case of aldehyde catalysis, results suggest that the rate determining step is the decomposition of the carbinolamine intermediate, whereas for catalysis by carbon dioxide, formation of the carbamate intermediate seems to be rate determining.en_NZ
dc.formatpdfen_NZ
dc.identifier.urihttps://ir.wgtn.ac.nz/handle/123456789/23225
dc.languageen_NZ
dc.language.isoen_NZ
dc.publisherTe Herenga Waka—Victoria University of Wellingtonen_NZ
dc.rights.holderAll rights, except those explicitly waived, are held by the Authoren_NZ
dc.rights.licenseAuthor Retains Copyrighten_NZ
dc.rights.urihttps://www.wgtn.ac.nz/library/about-us/policies-and-strategies/copyright-for-the-researcharchive
dc.subjectHydrolysisen_NZ
dc.subjectChemistryen_NZ
dc.titleKinetic studies of the hydrolysis of α-amino acid estersen_NZ
dc.typeTexten_NZ
thesis.degree.disciplineChemistryen_NZ
thesis.degree.grantorTe Herenga Waka—Victoria University of Wellingtonen_NZ
thesis.degree.levelMastersen_NZ
thesis.degree.nameMaster of Scienceen_NZ
vuwschema.type.vuwAwarded Research Masters Thesisen_NZ

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