dc.contributor.author |
Mansell, James Lindsay |
|
dc.date.accessioned |
2011-12-13T21:26:37Z |
|
dc.date.accessioned |
2022-10-31T21:20:56Z |
|
dc.date.available |
2011-12-13T21:26:37Z |
|
dc.date.available |
2022-10-31T21:20:56Z |
|
dc.date.copyright |
1957 |
|
dc.date.issued |
1957 |
|
dc.identifier.uri |
https://ir.wgtn.ac.nz/handle/123456789/27082 |
|
dc.description.abstract |
The aim of this research is the synthesis of the naturally occurring tropolone, nootkatin.
An account is given of a number of methods used in attempting to lengthen the dicarboxylic acid chain in a δ-lactam acid (2-oxo-4-isopropylpiperidine-5-carboxylic acid) with a view to subsequent cyclisation to a seven-membered carbon ring.
The preparation of a malonate keto ester is described and its intended use in the synthesis of nootkatin is outlined. It is unlikely a better intermediate than the δ-lactam acid could be devised since it has suitable groups in the correct relative positions for an unambiguous synthesis.
The probable stereochemistry of the δ-lactam acid and its derivatives is also discussed. |
en_NZ |
dc.format |
pdf |
en_NZ |
dc.language |
en_NZ |
|
dc.language.iso |
en_NZ |
|
dc.publisher |
Te Herenga Waka—Victoria University of Wellington |
en_NZ |
dc.title |
Studies related to a synthetic approach to nootkatin |
en_NZ |
dc.type |
Text |
en_NZ |
vuwschema.type.vuw |
Awarded Research Masters Thesis |
en_NZ |
thesis.degree.discipline |
Chemistry |
en_NZ |
thesis.degree.grantor |
Te Herenga Waka—Victoria University of Wellington |
en_NZ |
thesis.degree.level |
Masters |
en_NZ |
thesis.degree.name |
Master of Science |
en_NZ |